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Nuclear Energy Conference & Expo (NECX)
September 8–11, 2025
Atlanta, GA|Atlanta Marriott Marquis
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Chris Wagner: The role of Eden Radioisotopes in the future of nuclear medicine
Chris Wagner has more than 40 years of experience in nuclear medicine, beginning as a clinical practitioner before moving into leadership roles at companies like Mallinckrodt (now Curium) and Nordion. His knowledge of both the clinical and the manufacturing sides of nuclear medicine laid the groundwork for helping to found Eden Radioisotopes, a start-up venture that intends to make diagnostic and therapeutic raw material medical isotopes like molybdenum-99 and lutetium-177.
Christine Mansilla
Nuclear Technology | Volume 162 | Number 3 | June 2008 | Pages 323-332
Technical Paper | Thermal Hydraulics | doi.org/10.13182/NT08-A3959
Articles are hosted by Taylor and Francis Online.
Generation IV nuclear reactors will not be implemented unless they enable lower production costs than with the current systems. In such a context, considering only technical issues such as the performances of the plant is not entirely satisfactory since maximizing the system efficiency does not guarantee a minimum cost. Consequently, a technoeconomic optimization method was developed and then applied to the power conversion system of a very high temperature reactor.Technoeconomic optimization consists in minimizing an objective function that depends on technical and economic variables. The advantage of the technoeconomic optimization compared to classical optimizations based on the efficiency is that it can take into account both investment costs and operating costs.A technoeconomic model was implemented in a specific optimization software named Vizir, which is based on genetic algorithms. The calculation of the thermodynamic cycle is performed by a software named Tugaz.The results are the values of the decision variables that lead to a minimum cost, according to the model. The total production cost is evaluated. The consequences of different modifications of the model are discussed.