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Reimagining nuclear materials for the future of medicine
Nuclear medicine has come a long way since Henri Becquerel first observed the penetrating energy of radioactive materials in 1896. Today, technetium-99m alone is used in more than 40 million diagnostic procedures every year—from cardiovascular imaging and bone scans to cancer detection—making it the undisputed workhorse of nuclear medicine. That single statistic tells you something important: An enormous portion of modern diagnostic medicine rests on a surprisingly narrow foundation, one built around a small number of aging research reactors that were never originally designed for continuous isotope production.
T. W. Kerlin, G. C. Zwingelstein, B. R. Upadhyaya
Nuclear Technology | Volume 36 | Number 1 | November 1977 | Pages 7-38
Technical Paper | Critical Review | doi.org/10.13182/NT77-A31954
Articles are hosted by Taylor and Francis Online.
A great deal of information about a nuclear power plant and the coefficients that describe it is contained in the data that can be collected in plant transients. Much of this information is difficult or impossible to obtain from steady-state measurements. Significant advances have been made in developing techniques to extract the desired performance-related or safety-related information from transient data records. Techniques are available for determining such specific design parameters as reactivity feedback coefficients or heat transfer coefficients. Models, either derived from physical principles or developed empirically, can be tuned by comparison with plant data, and they are capable of very accurate predictions of plant responses to disturbances. Efficient methods, with on-line computing capability, can track performance-related parameters to yield information on plant conditions for surveillance purposes. Methods such as these provide expanded capability for extracting useful information from operating plants.