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Nuclear Energy Conference & Expo (NECX)
September 8–11, 2025
Atlanta, GA|Atlanta Marriott Marquis
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Chris Wagner: The role of Eden Radioisotopes in the future of nuclear medicine
Chris Wagner has more than 40 years of experience in nuclear medicine, beginning as a clinical practitioner before moving into leadership roles at companies like Mallinckrodt (now Curium) and Nordion. His knowledge of both the clinical and the manufacturing sides of nuclear medicine laid the groundwork for helping to found Eden Radioisotopes, a start-up venture that intends to make diagnostic and therapeutic raw material medical isotopes like molybdenum-99 and lutetium-177.
Francesco D'Auria, Walter Giannotti
Nuclear Technology | Volume 131 | Number 2 | August 2000 | Pages 159-196
Technical Paper | Reactor Safety | doi.org/10.13182/NT00-5
Articles are hosted by Taylor and Francis Online.
The internal assessment of uncertainty is a desirable capability for thermal-hydraulic system codes. This consists of the possibility of obtaining proper uncertainty bands each time a nuclear plant transient scenario is calculated. A methodology suitable for introducing such a capability into a system code is discussed. At the basis of the derivation of the code with (the capability of) internal assessment of uncertainty (CIAU), there is the uncertainty methodology based on the accuracy extrapolation (UMAE), previously proposed by the University of Pisa, although other uncertainty methodologies can be used for the same purpose.The idea of the CIAU is the identification and the characterization of standard plant statuses and the association of uncertainty to each status. One hypercube and one time interval identify the plant status. Quantity and time uncertainties are combined for each plant status.The recently released U.S. Nuclear Regulatory Commission RELAP5/MOD3.2 system code constitutes the CIAU. This is used for showing the applicability of the proposed method. The derivation of the methodology is discussed, and reference results of pressurized water reactor plant transients are shown bounded by the CIAU-calculated uncertainty bands.