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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Ryoichi Kondo, Tomohiro Endo, Akio Yamamoto, Satoshi Takeda, Hiroki Koike, Kazuya Yamaji, Daisuke Sato
Nuclear Science and Engineering | Volume 195 | Number 7 | July 2021 | Pages 694-716
Technical Paper | doi.org/10.1080/00295639.2020.1863066
Articles are hosted by Taylor and Francis Online.
A Resonance calculation using energy Spectrum Expansion (RSE) method is newly proposed in this paper. In this method, ultra-fine-group (UFG) spectra appearing in a resonance calculation are expanded by orthogonal bases on energy, which are extracted from the UFG spectra obtained in homogeneous geometry with various background cross sections using singular value decomposition and low-rank approximation. Namely, this method is based on the concept of a reduced order model. A neutron transport equation for flux moments (expansion coefficients) similar to the conventional one is derived and is numerically solved. This method applies to two benchmark problems in which a resonance interference effect and spatial self-shielding effect can appear. The results indicate that this method accurately predicts the reference effective cross sections and reaction rates obtained from direct UFG calculation in heterogeneous geometry.