A model calculation of neutron activation cross sections is carried out with SINCROS-II for all stable isotopes of molybdenum. Results of the calculation are compared with experimental data, which were measured over the wide range from threshold to 20 MeV. The general agreement between the calculated and experimental cross sections is good, but some cross sections remain in significant disagreement. The calculational method is applicable to the estimation of production cross sections for the long-lived radioactive nuclides.