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Conference Spotlight
Nuclear Energy Conference & Expo (NECX)
September 8–11, 2025
Atlanta, GA|Atlanta Marriott Marquis
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Chris Wagner: The role of Eden Radioisotopes in the future of nuclear medicine
Chris Wagner has more than 40 years of experience in nuclear medicine, beginning as a clinical practitioner before moving into leadership roles at companies like Mallinckrodt (now Curium) and Nordion. His knowledge of both the clinical and the manufacturing sides of nuclear medicine laid the groundwork for helping to found Eden Radioisotopes, a start-up venture that intends to make diagnostic and therapeutic raw material medical isotopes like molybdenum-99 and lutetium-177.
W. Knop, H. B. Stuhrmann, R. Wagner, M. Wenkow-EsSouni, J. Zhao, O. Schärpf, M. Krumpolc, K. H. Nierhaus, T. O. Niinikoski, A. Rijllart
Nuclear Science and Engineering | Volume 110 | Number 4 | April 1992 | Pages 316-329
Technical Paper | doi.org/10.13182/NSE92-A23906
Articles are hosted by Taylor and Francis Online.
Polarized neutron scattering from clusters of polarized proton spins in solid material provides a new contrast variation method. Frozen solutions of apoferritin and of the large subunit of Escherichia coli ribosomes in a mixture of heavy water and deuterated glycerol have been studied at the conditions of dynamic nuclear spin polarization (H = 2.5 T, T < 1K, 4-mm microwave irradiation). The three basic scattering functions of contrast variation were derived by varying polarized neutron scattering with the polarization of target nuclei. They agree with results obtained from neutron scattering in H2O/D2O mixtures at room temperature. Furthermore, the proton spins appear to be polarized uniformly, at least to a structural resolution of 40 Å. This is an important prerequisite for the in situ structure determination of macromolecular labels in larger host particles.