The shielding and containment criteria for the Transuranium Processing Plant obtained by calculations and experiments are given. The shield evaluation studies (for cell walls, cell windows, and fission source carriers) utilized experiments at the ORNL Lid Tank Shielding Facility and IBM-7090 computer calculations for determination of neutron transport, neutron activation, and gamma penetration. These studies also included an evaluation of the effects of credible accidents occurring in the facility.