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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
Y. Harima, Y. Sakamoto, S. Tanaka, M. Kawai
Nuclear Science and Engineering | Volume 94 | Number 1 | September 1986 | Pages 24-35
Technical Paper | doi.org/10.13182/NSE86-A17113
Articles are hosted by Taylor and Francis Online.
A geometric-progression (G-P) method formula, Br = 1 + (B − 1) · (Kx − 1)/(K − 1), accurately represents the buildup factor data as a function of distance for the following reasons: 1. The value of parameter B corresponds to that of the buildup factor at 1 mfp, which is the integration of a basic spectrum for a specified material and for a specified source energy. 2. The variation of parameter K with penetration represents the photon dose multiplication and the change in the shape of the spectrum. Exposure buildup factors for point isotropic sources in an infinite medium approximated by the G-P fitting parameters are in good agreement with the basic data calculated by the PALLAS code, including that of boron for low energies, and of lead, including the effects of bremsstrahlung and fluorescence. The validity of using the G-P parameters to interpolate the buildup factor in μr and in E is ascertained. Furthermore, the extrapolation to the buildup data for depths above 40 mfp is examined.