A laser-induced cold fusion reaction has been obtained in Ti-H2-D2-T2 systems. Correlations are found among gamma-ray pulses, neutron emission pulses, and phase transitions in the Ti-D2 system. No thermal effect is observed. Gamma-ray fluxes of ∼5 × 103 gamma/s and neutron emission of ∼2 × 102 n/s in pulses of <0.5 s have been obtained. The possibility of laser generation of gamma rays in the cold fusion reaction is discussed, as are aspects of laser-induced phase transitions in metal-gas systems.