The activation characteristics of several materials were evaluated for short term as well as long term impacts on the operation of the IGNITEX device. Candidate design materials for the vacuum wall, magnet, and the cryostat outer covering were studied for their activation levels over the operational history of the IGNITEX fusion experiment and for 100 years beyond shutdown. Although DT fuel was of primary interest in this study, activation from DD shots also was investigated for the primary vacuum wall candidate material. Activation results showed for that the type of material chosen for each component can significantly affect the amount and the disposal classification of the radioactive wastes generated by the IGNITEX device.