We explore the utility and feasibility of neutral beams of A ≥ 6 amu formed from negative ions, and also of D0 formed from D−. The negative ions would be accelerated to ∼1 to 2 MeV/amu and neutralized, whereupon the neutral atoms would be used to heat and perhaps to drive current in magnetically confined plasmas. Such beams appear feasible and offer the promise of significant advantages relative to conventional neutral beams based on positive deuterium ions at ∼150 keV.