It is demonstrated that the deformation of the crystalline lattice at room temperature can influence the process of fusion of the deuterons introduced into the lattice by deuterium loading. In fact, calculating the probability of deuteron-plasmon fusion within a microcrack, showed, together with the enhancement of the tunneling effect, an increase of at least one to three orders of magnitude compared to the probability of fusion on the surface of the lattice. These phenomena open the way to the theoretical hypothesis that a kind of chain reaction, catalyzed by the microcracks produced in the structure as a result of deuterium loading, can favor the process.