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Radium sources yield cancer-fighting Ac-225 in IAEA program
The International Atomic Energy Agency has reported that, to date, 14 countries have made 14 transfers of disused radium to be recycled for use in advanced cancer treatments under the agency’s Global Radium-226 Management Initiative. Through this initiative, which was launched in 2021, legacy radium-226 from decades-old medical and industrial sources is used to produce actinium-225 radiopharmaceuticals, which have shown effectiveness in the treatment of patients with breast and prostate cancer and certain other cancers.
H. Huang, H. W. Xu, K. P. Youngblood, D. R. Wall, R. B. Stephens, K. A. Moreno, A. Nikroo, K. J. Wu, M. Wang, A. V. Hamza
Fusion Science and Technology | Volume 63 | Number 2 | March-April 2013 | Pages 190-201
Technical Paper | Selected papers from 20th Target Fabrication Meeting, May 20-24, 2012, Santa Fe, NM, Guest Editor: Robert C. Cook | doi.org/10.13182/FST13-TFM20-24
Articles are hosted by Taylor and Francis Online.
The National Ignition Facility point design uses a five-layer capsule to modify the X-ray absorption in order to achieve optimized shock timing. A stepwise copper dopant design defines the layer structure; however, the as-deposited Cu distribution is significantly altered during the CH mandrel removal by pyrolysis. The changes are significant: (a) Cu diffuses on average several microns, a distance more than an order of magnitude larger than predicted from the bulk diffusion data, and (b) the Cu distribution, as a result of diffusion, is highly heterogeneous, introducing a local variation of [approximately]0.06 at. % near the original layer interface. In this study, we developed quantitative techniques to measure Cu diffusion and explored its correlation to beryllium microstructures. Plausible diffusion mechanisms and mitigation methods will be discussed. These findings will enable more accurate evaluation of the expected target performance.