The compact (R0~1.2-1.3m) Fusion Nuclear Science Facility (FNSF) is aimed at providing a fully integrated, continuously driven fusion nuclear environment of copious fusion neutrons. This facility would be used to test, discover, and understand the complex challenges of fusion plasma material interactions, nuclear material interactions, tritium fuel management, and power extraction. Such a facility properly designed would provide, initially at the JET-level plasma pressure (~30%T2) and conditions (e.g., Hot-Ion H-Mode, Q<1)), an outboard fusion neutron flux of 0.25 MW/m2 while requiring a fusion power of ~19 MW. If and when this research is successful, its performance can be extended to 1 MW/m2 and ~76 MW by reaching for twice the JET plasma pressure and Q. High-safety factor q and moderate-plasmas are used to minimize or eliminate plasma-induced disruptions, to deliver reliably a neutron fluence of 1 MW-yr/m2 and a duty factor of 10% presently anticipated for the FNS research. Success of this research will depend on achieving time-efficient installation and replacement of all internal components using remote handling (RH). This in turn requires modular designs for the internal components, including the single-turn toroidal field coil center-post. These device goals would further dictate placement of support structures and vacuum weld seals behind the internal and shielding components. If these goals could be achieved, the FNSF would further provide a ready upgrade path to the Component Test Facility (CTF), which would aim to test, for 6 MW-yr/m2 and 30% duty cycle, the demanding fusion nuclear engineering and technologies for DEMO. This FNSF-CTF would thereby complement the ITER Program, and support and help mitigate the risks of an aggressive world fusion DEMO R&D Program. The key physics and technology research needed in the next decade to manage the potential risks of this FNSF are identified.