Data for 40 of the 71 isotopes/elements in FENDL-2.1 were taken from ENDF/B-VI.8. Following the release of ENDF/B-VII.0 we performed a preliminary assessment for changes made in data of these 40 isotopes/elements. We compared the relevant cross sections in the two libraries. In addition, we carried out MCNP calculations for a calculational benchmark representative of an early ITER design that was utilized during the FENDL development process. In addition, we performed 3-D calculations for an inertial fusion power plant conceptual design. It is concluded that modifying FENDL-2.1 to include the most recent ENDF/B-VII.0 is not urgently needed for ITER analysis. On the other hand, the larger changes in calculated ICF target neutronics parameters and tritium breeding ratio confirm the need for updating FENDL-2.1 for use in analysis of fusion systems beyond ITER. Additional calculations are in progress for integral experimental benchmarks to fully understand the impact of data changes introduced in ENDF/B-VII.0.