The deuterium-tritium (D-T) experimental program on the Tokamak Fusion Test Reactor (TFTR) is underway and routine tritium operations have been established. The technology upgrades made to the TFTR facility have been demonstrated to be sufficient for supporting both operations and maintenance for an extended D-T campaign. To date fusion power has been increased to ∼9 MW and several physics results of importance to the D-T reactor regime have been obtained: electron temperature, ion temperature, and plasma stored energy all increase substantially in the D-T regime relative to the D-D regime at the same neutral beam power and comparable limiter conditioning; possible alpha electron heating is indicated and energy confinement improvement with average ion mass is observed; and alpha particle losses appear to be classical with no evidence of TAE mode activity up to the PFUS ∼ 6 MW level. Instability in the TAE mode frequency range has been observed at PFUS > 7 MW and its effect on performance is under investigation. Preparations are underway to enhance the alpha particle density further by increasing fusion power and by extending the neutral beam pulse length to permit alpha particle effects of relevance to the ITER regime to be more fully explored.