New target designs for the Omega upgrade laser and ignition targets in the National Ignition Facility (NIF) require thick (80 – 100 µm) cryogenic fuel layers. The Omega upgrade target will require cryogenic handling after initial fill because of the high fill pressures and the thin capsule walls. For the NIF indirectly driven targets, a larger capsule size and new materials offer hope that they can be built, filled and stored in a manner similar to the targets used in the Nova facility without requiring cryogenic handling.