The Combined Electrolysis Catalytic Exchange (CECE) process, utilizing AECL's wetproofed catalyst, is ideally suited for extracting tritium from water because of its high isotopic separation factor and near-ambient operating conditions. Several CECE options are compared with the more conventional DW-VPCE arrangements for heavy water upgrading and detritiation of CANDU nuclear reactors and for detritiation of fusion facilities such as ITER. For both applications, CECE offers a more economical alternative over conventional technology. Experimental data on catalyst activity and lifetime are also presented and past commercial applications of the AECL catalyst are reviewed. AECL has recently committed to assembly of a CECE upgrading/detritiation demonstration facility.